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Myelodysplastic Syndromes17m 59s
Genomics of AML -Therapeutic and Prognostic Implications
~40% of AML patients have targetable mutations. Younger patients often have FLT3-ITD or FLT3- TKD mutation. Mutations IDH-1 , IDH-2 & t-53 mutations are more common in elderly patients.
idh 1& 2 mutations
flt3-tkd mutations
bcl2 inhibtors
genomics of aml
1
Genomics of AML -Therapeutic and Prognostic...
Myelodysplastic Syndromes3m 14s
Low Risk MDS - Key Practice Points
Myelodysplastic Syndromes (MDS) or Myeloproliferative Neoplasms show considerable heterogeneity with respect to presence of anemia , cytopenia & molecular features.
ipss -m
low risk
molecular features
1
Low Risk MDS - Key Practice Points
Breast Cancer3m 36s
Tumor Infiltrating Lymphocytes as Predictive Biomarker in Breast Cancer
Immune cells known as tumor-infiltrating lymphocytes (TILs) are thought to be a promising, affordable biomarker with prognostic and predictive potential.
tumor-infiltrating lymphocytes (tils)
promising biomarker
1
Tumor Infiltrating Lymphocytes as Predictive...
Multiple-Myeloma0m 53s
Importance of identifying High Risk Patients in Multiple Myeloma
High risk disease is observed in 30% of Myeloma Cases. Identification of high-risk patients is important as proportion of high-risk cases increase with relapses and can lead to significant mortality.
high risk myeloma
1
Importance of identifying High Risk Patients in...
"NA"11m 43s
Sequencing of treatment for Her2 positive MBC in 2022
Noteworthy treatment options added in the treatment guidelines for Her2 positive MBC are Trastuzumab Deruxtecan (TDXd) and combination of Trastuzumab + Capecitabine +Tucatinib.
brain metastases
her2 positive mbc
trastuzumab deruxtecan
tucatinib
1
Sequencing of treatment for Her2 positive MBC in...
Multiple Myeloma4m 12s
Key Practice Points -Myeloma Related Renal Impairment
In patients with renal impairment primary goal is improvement of Renal Function which is associated with improved treatment outcomes. 50% of patients present renal impairment and renal impairment is severe in 15% of patients.
myeloma
renal impairment
key practice points
1
Key Practice Points -Myeloma Related Renal...
Multiple Myeloma10m 40s
Recommendations -Management of Myeloma Related Renal Impairment
Supportive Care, Mechanical Approach and Systemic Antimyeloma treatment are 3 pillars of management of Myeloma related renal impairment. In supportive care prompt initiation of high fluid administration, appropriate use of Bisphosphonates can help.
myeloma
renal impairment
lancet guidelines
1
Recommendations -Management of Myeloma Related...
Breast Cancer29m 30s
SABCS Update 2022
Summary of Key Abstracts from SABCS 2022
recurrence score
tailor-x
destiny breast 03
adjuvant cdk4/6 inhibitor
antibody drug conjugates
1
SABCS Update 2022
Myelodysplastic Syndromes31m 24s
Improving Diagnosis of MDS -Innovative Solutions
Modern Web -Based digital tools based on 10 routinely used clinical parameters and Gradient Based Model can help in non-invasive diagnosis of MDS.
mds diagnosis
web based diagnosis
her2negative mbc
1
Improving Diagnosis of MDS -Innovative Solutions
Breast Cancer8m 55s
Understanding HER-2 Low Breast Cancer Entity & Treatment Strategy
Tumors with a HER-2 immunohistochemistry (IHC) score of 1 + or 2 + and a negative molecular reflex test have been classified as HER2-low Breast Cancers.
trastuzumab-deruxtecan (t-dxd)
her2 low breast cancers
1
Understanding HER-2 Low Breast Cancer Entity &...
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