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Breast Cancer3m 36s
Tumor Infiltrating Lymphocytes as Predictive Biomarker in Breast Cancer
Immune cells known as tumor-infiltrating lymphocytes (TILs) are thought to be a promising, affordable biomarker with prognostic and predictive potential.
tumor-infiltrating lymphocytes (tils)
promising biomarker
1
Tumor Infiltrating Lymphocytes as Predictive...
Multiple Myeloma4m 12s
Key Practice Points -Myeloma Related Renal Impairment
In patients with renal impairment primary goal is improvement of Renal Function which is associated with improved treatment outcomes. 50% of patients present renal impairment and renal impairment is severe in 15% of patients.
myeloma
renal impairment
key practice points
1
Key Practice Points -Myeloma Related Renal...
Prostate Cancer11m 38s
Treatment Intensification in Metastatic Castration Sensitive Prostate Cancer
PEACE-1 clinical trial demonstrated that combining ADT and docetaxel with abiraterone acetate plus prednisone (AAP) improves both overall survival (OS) and radiographic progression-free-survival (rPFS) in men with de novo mCSPC.
treatment intensification
mhspc
triplet therapy
peace-1 clinical trial
1
Treatment Intensification in Metastatic Castration...
Oncology1m 36s
Enhancing Global Access to Cancer Medicines
Over the last decade we have seen emergence of increasing novel therapies like targeted therapy and immunotherapy & this has changed the natural history of disease for patients living with cancer including those with advanced disease.
biosimilars
access
generics
1
Enhancing Global Access to Cancer Medicines
Multiple Myeloma10m 40s
Recommendations -Management of Myeloma Related Renal Impairment
Supportive Care, Mechanical Approach and Systemic Antimyeloma treatment are 3 pillars of management of Myeloma related renal impairment. In supportive care prompt initiation of high fluid administration, appropriate use of Bisphosphonates can help.
myeloma
renal impairment
lancet guidelines
1
Recommendations -Management of Myeloma Related...
Breast Cancer8m 55s
Understanding HER-2 Low Breast Cancer Entity & Treatment Strategy
Tumors with a HER-2 immunohistochemistry (IHC) score of 1 + or 2 + and a negative molecular reflex test have been classified as HER2-low Breast Cancers.
trastuzumab-deruxtecan (t-dxd)
her2 low breast cancers
1
Understanding HER-2 Low Breast Cancer Entity &...
Myelodysplastic Syndromes3m 14s
Low Risk MDS - Key Practice Points
Myelodysplastic Syndromes (MDS) or Myeloproliferative Neoplasms show considerable heterogeneity with respect to presence of anemia , cytopenia & molecular features.
ipss -m
low risk
molecular features
1
Low Risk MDS - Key Practice Points
Multiple Myeloma7m 42s
MRD Assesment in Multiple Myeloma -Ready for Prime Time
Multiple Myeloma is an incurable disease with patients relapsing even after achieving deep responses. Minimal Residual Disease (MRD) represents a relatively new way of evaluating response to treatment.
minimum residual disease (mrd)
mrd negativity
multiple myeloma
1
MRD Assesment in Multiple Myeloma -Ready for Prime...
Prostate Cancer6m 59s
Managing Nonmetastatic Castration-Resistant Prostate Cancer (nmCRPC)
3 randomized clinical trials (SPRATAN- Apalutamide), (PROSPER -Enzalutamide) & (ARAMIS -Darolutamide) have shown consistent and almost similar benefit in Metastasis Free Survival in nmCRPC
nmcrpc
metastasis free survival
spartan
prosper & aramis clinical trial
1
Managing Nonmetastatic Castration-Resistant...
Breast Cancer11m 14s
Oral Selective Estrogen Receptor Degraders for ESR-1 Mutant Metastatic Breast Cancer
Endocrine therapy is the mainstay in the management of patients with Hormone receptor positive (ER+ve) Metastatic Breast Cancer. Tumor progression in ER+ve MBC could be attributed to genomic alterations such as ESR mutations.
biomarkers
esr1 mutation
fulvestrant
hormone receptor positive mbc
serd
1
Oral Selective Estrogen Receptor Degraders for...
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